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Molecular Structure of the Ingredients in the Pfizer-BioNTech Covid-19 Vaccine

The ingredients of each Covid-19 vaccine used in the USA have been published by the Food and Drug Administration (FDA).  However, only their...


The ingredients of each Covid-19 vaccine used in the USA have been published by the Food and Drug Administration (FDA).  However, only their names are given.  Here you will find the molecular structures of the ten (10) ingredients in the Pfizer-BioNTech vaccine.

The vaccine include the following ingredients:

  • mRNA (messenger RiboNucleic Acid)

    It is a single strand polymer that consists of monomers called nucleotides, which are copied from a segment of DNA. The general structure of RNA is shown below.

(Sponk/Wikimedia Commons)


  • ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)


  • 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide


  • 1,2-Distearoyl-sn-glycero-3- phosphocholine


  • Cholesterol


  • Potassium Chloride (KCl)

  • Monobasic potassium phosphate (KH2PO4)


  • Sodium chloride (NaCl)


  • Dibasic sodium phosphate dihydrate (Na2HPO4 . H2O)
  • Sucrose


Helpful References


Pfizer-BioNTech Covid-19 Vaccine, Facts Sheet for Recipients and Caregivers

Food and Drug Administration, May 11, 2021


Messenger ribonucleic acid

Biology Online


Understanding the nanotechnology in Covid-19 vaccines

CAS - American Chemical Society, Feb 18, 2021


Inside the new mRNA vaccines for COVID-19

UMass Medical School, Dec 18, 2020


mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

International Journal of Pharmaceutics, Vol 601, May 15, 2021, 120586

https://doi.org/10.1016/j.ijpharm.2021.120586